| Date | Location | Result | |
| Nov 13, 2021 | Rochester, NY | Hobart 31, Rochester 0 | Box score |
| Nov 06, 2021 | Oneonta, NY | Rochester 42, Hartwick 28 | Box score |
| Oct 30, 2021 | Canton, NY | St. Lawrence 34, Rochester 10 | Box score |
| Oct 23, 2021 | Rochester, NY | Union (NY) 35, Rochester 9 | Box score |
| Oct 16, 2021 | Buffalo, NY | Rochester 14, Buffalo State 7 | Box score |
| Oct 09, 2021 | Rochester, NY | Ithaca 37, Rochester 14 | Box score |
| Oct 02, 2021 | Troy, NY | Rensselaer 38, Rochester 22 | Box score |
| Sep 18, 2021 | Brockport, NY | SUNY Brockport 16, Rochester 7 | Box score |
| Sep 11, 2021 | Rochester, NY | Rochester 28, Alfred State 27 | Box score |
| Sep 04, 2021 | Rochester, NY | Case Western Reserve 27, Rochester 20 | Box score |